MSSNG (pronounced “missing”) is a groundbreaking collaboration between Autism Speaks, Verily, DNAstack, Hospital for Sick Children (SickKids), and the research community to create a comprehensive whole genome sequencing database on autism with phenotyping. MSSNG’s goal is to provide the best resources to enable the identification of many subtypes of autism, which may lead to better diagnostics, as well as personalized and more accurate treatments. Through an online application process, MSSNG provides whole genome sequencing of blood DNA (minimum 30x high-quality coverage) of 15,500+ individuals from families (Trios and Multiplex) from well-phenotyped cohorts entering into this study. The MSSNG database, built using the Google Cloud Platform and Google Genomics, intends to make its data as useful and widely accessible to researchers as possible, including access to local compute and storage resources, and providing genomic exploration tools for standard and custom analyses. Whole genome sequences and their annotations and phenotype data are being continually added and/or modified for access to researchers. MSSNG’s philosophy is to promote and enable open science research with...
Access requires approval by the data custodian. The collection's description and structure are public; querying the data requires an approved request.
MSSNG is published on Neuroscience AI.